Drug interactions
Idarubicin + Lasmiditan
Severity: Minor
Idarubicin and Lasmiditan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan inhibits intestinal P-glycoprotein, and idarubicin is a P-gp substrate. This could raise exposure after oral dosing, but idarubicin is usually given intravenously, so the effect is likely small.
What this interaction means in plain words
Idarubicin and Lasmiditan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Idarubicin belongs to Oncology; Lasmiditan belongs to Central Nervous System.
Why it happens
Lasmiditan inhibits P-gp efflux transport.
What to do
No routine change is needed with intravenous idarubicin; monitor blood counts as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Idarubicin
- Adenovirus types 4 and 7 live + Idarubicin Contraindicated
- Belatacept + Idarubicin Major
- Cyclophosphamide + Idarubicin Major
- Deferiprone + Idarubicin Major
- Dengue vaccine + Idarubicin Major
- Etrasimod + Idarubicin Major
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Idarubicin with Lasmiditan?
MediHelp rates the interaction as minor. Idarubicin and Lasmiditan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lasmiditan inhibits intestinal P-glycoprotein, and idarubicin is a P-gp substrate. This could raise exposure after oral dosing, but idarubicin is usually given intravenously, so the effect is likely small.
How serious is the interaction between Idarubicin and Lasmiditan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed with intravenous idarubicin; monitor blood counts as usual.
What other medicines interact with Idarubicin?
MediHelp also lists interactions of Idarubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclophosphamide. The full list is on the Idarubicin page.
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