Drug interactions
Iloperidone + Terbutaline
Severity: Moderate
Iloperidone and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloperidone prolongs the QT interval, and terbutaline can cause tachycardia, hypokalemia and arrhythmia. Combined use may raise the risk of QT-related ventricular arrhythmia, especially with other risk factors.
What this interaction means in plain words
Iloperidone and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iloperidone belongs to Central Nervous System; Terbutaline belongs to Respiratory.
Why it happens
Additive QT-prolonging and proarrhythmic effects; beta-2 agonist hypokalemia increases repolarization risk.
What to do
Check potassium and magnesium and obtain an ECG in patients with cardiac risk factors. Avoid adding further QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Other interactions of Iloperidone
- Iloperidone + Thioridazine Contraindicated
- Alfuzosin + Iloperidone Major
- Amiodarone + Iloperidone Major
- Amisulpride + Iloperidone Major
- Amitriptyline + Iloperidone Major
- Anagrelide + Iloperidone Major
Frequently asked questions
Can I take Iloperidone with Terbutaline?
MediHelp rates the interaction as moderate. Iloperidone and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloperidone prolongs the QT interval, and terbutaline can cause tachycardia, hypokalemia and arrhythmia. Combined use may raise the risk of QT-related ventricular arrhythmia, especially with other risk factors.
How serious is the interaction between Iloperidone and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and obtain an ECG in patients with cardiac risk factors. Avoid adding further QT-prolonging drugs.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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