Drug interactions
Iloprost inhaled + Tizanidine
Severity: Minor
Iloprost inhaled and Tizanidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled iloprost has some systemic vasodilatory effect and may lower blood pressure. Tizanidine may add to this and cause hypotension or dizziness.
What this interaction means in plain words
Iloprost inhaled and Tizanidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive blood pressure lowering from prostacyclin vasodilation and central alpha-2 agonism.
What to do
Monitor blood pressure and symptoms of hypotension when starting inhaled iloprost. Reduce the dose of one drug if symptoms occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tizanidine
- Ciprofloxacin + Tizanidine Contraindicated
- Fluvoxamine + Tizanidine Contraindicated
- Pefloxacin + Tizanidine Contraindicated
- Pipemidic acid + Tizanidine Contraindicated
- Benzhydrocodone / acetaminophen + Tizanidine Major
- Brexanolone + Tizanidine Major
Frequently asked questions
Can I take Iloprost inhaled with Tizanidine?
MediHelp rates the interaction as minor. Iloprost inhaled and Tizanidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled iloprost has some systemic vasodilatory effect and may lower blood pressure. Tizanidine may add to this and cause hypotension or dizziness.
How serious is the interaction between Iloprost inhaled and Tizanidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and symptoms of hypotension when starting inhaled iloprost. Reduce the dose of one drug if symptoms occur.
What other medicines interact with Tizanidine?
MediHelp also lists interactions of Tizanidine with, for example, Ciprofloxacin, Fluvoxamine, Pefloxacin. The full list is on the Tizanidine page.
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