Drug interactions
Imidapril + Insulin aspart
Severity: Minor
Imidapril and Insulin aspart: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors such as imidapril can improve insulin sensitivity and may enhance the glucose-lowering effect of insulin. This occasionally leads to hypoglycemia, particularly after starting the ACE inhibitor.
What this interaction means in plain words
Imidapril and Insulin aspart have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Imidapril belongs to Cardiovascular; Insulin aspart belongs to Endocrine.
Why it happens
ACE inhibition may increase insulin sensitivity, possibly via increased bradykinin and improved peripheral glucose uptake.
What to do
Monitor blood glucose when imidapril is started or the dose is changed, and reduce the insulin dose if hypoglycemia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin aspart
Other interactions of Imidapril
- Amiloride + Imidapril Major
- Eplerenone + Imidapril Major
- Imidapril + Lithium Major
- Imidapril + Pregabalin Major
- Imidapril + Spironolactone Major
- Imidapril + Triamterene Major
Frequently asked questions
Can I take Imidapril with Insulin aspart?
MediHelp rates the interaction as minor. Imidapril and Insulin aspart have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors such as imidapril can improve insulin sensitivity and may enhance the glucose-lowering effect of insulin. This occasionally leads to hypoglycemia, particularly after starting the ACE inhibitor.
How serious is the interaction between Imidapril and Insulin aspart?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when imidapril is started or the dose is changed, and reduce the insulin dose if hypoglycemia develops.
What other medicines interact with Insulin aspart?
MediHelp also lists interactions of Insulin aspart with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin aspart page.
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