Drug interactions
Indacaterol-glycopyrronium + Meclizine
Severity: Minor
Indacaterol-glycopyrronium and Meclizine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Meclizine is an antihistamine with anticholinergic activity, which adds to the antimuscarinic effect of glycopyrronium. Dry mouth, urinary retention, constipation and drowsiness may be more pronounced.
What this interaction means in plain words
Indacaterol-glycopyrronium and Meclizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Indacaterol-glycopyrronium belongs to Respiratory; Meclizine belongs to Respiratory.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for anticholinergic symptoms, particularly in older adults or those with prostatic hypertrophy or glaucoma. Use the lowest effective meclizine dose.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Meclizine
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Meclizine?
MediHelp rates the interaction as minor. Indacaterol-glycopyrronium and Meclizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Meclizine is an antihistamine with anticholinergic activity, which adds to the antimuscarinic effect of glycopyrronium. Dry mouth, urinary retention, constipation and drowsiness may be more pronounced.
How serious is the interaction between Indacaterol-glycopyrronium and Meclizine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic symptoms, particularly in older adults or those with prostatic hypertrophy or glaucoma. Use the lowest effective meclizine dose.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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