Drug interactions
Indacaterol inhaled + Mefloquine
Severity: Moderate
Indacaterol inhaled and Mefloquine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mefloquine can prolong the QT interval, and high-dose indacaterol can affect QTc and heart rate. Together they may modestly raise arrhythmia risk.
What this interaction means in plain words
Indacaterol inhaled and Mefloquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic QT effects.
What to do
Monitor ECG in patients with cardiac risk factors. Correct potassium and magnesium abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mefloquine
- Arsenic trioxide + Mefloquine Contraindicated
- Dronedarone + Mefloquine Contraindicated
- Ibutilide + Mefloquine Contraindicated
- Levoketoconazole + Mefloquine Contraindicated
- Mefloquine + Nilotinib Contraindicated
- Mefloquine + Pimozide Contraindicated
Frequently asked questions
Can I take Indacaterol inhaled with Mefloquine?
MediHelp rates the interaction as moderate. Indacaterol inhaled and Mefloquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mefloquine can prolong the QT interval, and high-dose indacaterol can affect QTc and heart rate. Together they may modestly raise arrhythmia risk.
How serious is the interaction between Indacaterol inhaled and Mefloquine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG in patients with cardiac risk factors. Correct potassium and magnesium abnormalities.
What other medicines interact with Mefloquine?
MediHelp also lists interactions of Mefloquine with, for example, Arsenic trioxide, Dronedarone, Ibutilide. The full list is on the Mefloquine page.
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