Drug interactions
Indacaterol inhaled + Moxifloxacin
Severity: Moderate
Indacaterol inhaled and Moxifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol, a long-acting beta2 agonist, can prolong the QT interval and cause hypokalemia, and moxifloxacin adds its own QT effect. The combined risk of ventricular arrhythmia may be increased, especially in patients with cardiac disease.
What this interaction means in plain words
Indacaterol inhaled and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta2-agonist-induced hypokalemia and sympathetic stimulation.
What to do
Monitor the ECG and serum potassium in patients with cardiac disease or other QT risk factors. Consider an alternative antibiotic if risk is high.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Indacaterol inhaled with Moxifloxacin?
MediHelp rates the interaction as moderate. Indacaterol inhaled and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol, a long-acting beta2 agonist, can prolong the QT interval and cause hypokalemia, and moxifloxacin adds its own QT effect. The combined risk of ventricular arrhythmia may be increased, especially in patients with cardiac disease.
How serious is the interaction between Indacaterol inhaled and Moxifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the ECG and serum potassium in patients with cardiac disease or other QT risk factors. Consider an alternative antibiotic if risk is high.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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