Drug interactions
Influenza virus vaccine quadrivalent recombinant + Mycophenolate mofetil
Severity: Minor
Influenza virus vaccine quadrivalent recombinant and Mycophenolate mofetil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mycophenolate can lower the antibody response to influenza vaccination. The recombinant vaccine is non-live and safe, but protection may be reduced.
What this interaction means in plain words
Influenza virus vaccine quadrivalent recombinant and Mycophenolate mofetil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic antagonism: inhibition of lymphocyte proliferation reduces vaccine immunogenicity.
What to do
Vaccinate as recommended, since benefit outweighs reduced response. Do not rely solely on vaccination; consider early treatment of influenza and vaccination of close contacts.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Frequently asked questions
Can I take Influenza virus vaccine quadrivalent recombinant with Mycophenolate mofetil?
MediHelp rates the interaction as minor. Influenza virus vaccine quadrivalent recombinant and Mycophenolate mofetil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mycophenolate can lower the antibody response to influenza vaccination. The recombinant vaccine is non-live and safe, but protection may be reduced.
How serious is the interaction between Influenza virus vaccine quadrivalent recombinant and Mycophenolate mofetil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as recommended, since benefit outweighs reduced response. Do not rely solely on vaccination; consider early treatment of influenza and vaccination of close contacts.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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