Drug interactions
Influenza virus vaccine trivalent adjuvanted + Mycophenolate mofetil
Severity: Moderate
Influenza virus vaccine trivalent adjuvanted and Mycophenolate mofetil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mycophenolate can reduce antibody responses to influenza vaccine, so protection may be incomplete. The vaccine is inactivated and safe, and vaccination is still recommended in transplant patients.
What this interaction means in plain words
Influenza virus vaccine trivalent adjuvanted and Mycophenolate mofetil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Inhibition of lymphocyte proliferation blunts the vaccine immune response.
What to do
Continue to vaccinate annually, ideally before transplant or intensified immunosuppression, and consider an additional dose or high-dose product where guidelines advise.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Frequently asked questions
Can I take Influenza virus vaccine trivalent adjuvanted with Mycophenolate mofetil?
MediHelp rates the interaction as moderate. Influenza virus vaccine trivalent adjuvanted and Mycophenolate mofetil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mycophenolate can reduce antibody responses to influenza vaccine, so protection may be incomplete. The vaccine is inactivated and safe, and vaccination is still recommended in transplant patients.
How serious is the interaction between Influenza virus vaccine trivalent adjuvanted and Mycophenolate mofetil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Continue to vaccinate annually, ideally before transplant or intensified immunosuppression, and consider an additional dose or high-dose product where guidelines advise.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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