Drug interactions
Insulin aspart + Tipranavir
Severity: Moderate
Insulin aspart and Tipranavir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tipranavir, like other HIV protease inhibitors, can cause insulin resistance and hyperglycemia. Insulin requirements may increase.
What this interaction means in plain words
Insulin aspart and Tipranavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin aspart belongs to Endocrine; Tipranavir belongs to Anti Virals.
Why it happens
Protease inhibitors reduce peripheral glucose uptake and insulin signaling, producing insulin resistance.
What to do
Monitor blood glucose when tipranavir is started or stopped. Adjust the insulin aspart dose according to results.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin aspart
Other interactions of Tipranavir
- Alfuzosin + Tipranavir Contraindicated
- Amiodarone + Tipranavir Contraindicated
- Atorvastatin + Tipranavir Contraindicated
- Avanafil + Tipranavir Contraindicated
- Cisapride + Tipranavir Contraindicated
- Colchicine + Tipranavir Contraindicated
Frequently asked questions
Can I take Insulin aspart with Tipranavir?
MediHelp rates the interaction as moderate. Insulin aspart and Tipranavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tipranavir, like other HIV protease inhibitors, can cause insulin resistance and hyperglycemia. Insulin requirements may increase.
How serious is the interaction between Insulin aspart and Tipranavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when tipranavir is started or stopped. Adjust the insulin aspart dose according to results.
What other medicines interact with Insulin aspart?
MediHelp also lists interactions of Insulin aspart with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin aspart page.
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