Drug interactions
Insulin degludec-liraglutide + Irbesartan
Severity: Minor
Insulin degludec-liraglutide and Irbesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and slightly enhance the glucose-lowering effect of insulin and liraglutide. Hypoglycemia is uncommon.
What this interaction means in plain words
Insulin degludec-liraglutide and Irbesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Insulin degludec-liraglutide belongs to Endocrine; Irbesartan belongs to Cardiovascular.
Why it happens
Possible improvement in insulin sensitivity by angiotensin II receptor blockade, giving additive glucose lowering.
What to do
Monitor glucose when irbesartan is started or stopped. Reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Irbesartan
- Aliskiren + Irbesartan Contraindicated
- Irbesartan + Sparsentan Contraindicated
- Amifostine + Irbesartan Major
- Amiloride + Irbesartan Major
- Amlodipine-benazepril + Irbesartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Irbesartan Major
Frequently asked questions
Can I take Insulin degludec-liraglutide with Irbesartan?
MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Irbesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and slightly enhance the glucose-lowering effect of insulin and liraglutide. Hypoglycemia is uncommon.
How serious is the interaction between Insulin degludec-liraglutide and Irbesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when irbesartan is started or stopped. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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