Drug interactions
Insulin degludec-liraglutide + Ziprasidone
Severity: Minor
Insulin degludec-liraglutide and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ziprasidone can affect glucose regulation and has been associated with hyperglycemia, though less than some other atypical antipsychotics. This may modestly reduce the effect of insulin degludec-liraglutide.
What this interaction means in plain words
Insulin degludec-liraglutide and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Insulin degludec-liraglutide belongs to Endocrine; Ziprasidone belongs to Central Nervous System.
Why it happens
Atypical antipsychotics may induce insulin resistance and impair insulin secretion, opposing antidiabetic drugs.
What to do
Monitor blood glucose and HbA1c after starting ziprasidone. Adjust the antidiabetic dose if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Frequently asked questions
Can I take Insulin degludec-liraglutide with Ziprasidone?
MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ziprasidone can affect glucose regulation and has been associated with hyperglycemia, though less than some other atypical antipsychotics. This may modestly reduce the effect of insulin degludec-liraglutide.
How serious is the interaction between Insulin degludec-liraglutide and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c after starting ziprasidone. Adjust the antidiabetic dose if control worsens.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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