Drug interactions
Insulin glargine + Methyltestosterone
Severity: Moderate
Insulin glargine and Methyltestosterone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgens can improve insulin sensitivity and lower blood glucose, which may increase the risk of hypoglycemia in insulin-treated patients. The effect is usually modest but can matter when insulin doses are tightly titrated.
What this interaction means in plain words
Insulin glargine and Methyltestosterone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Androgens may enhance insulin sensitivity and alter glucose metabolism, adding to the effect of insulin.
What to do
Monitor blood glucose when starting or stopping methyltestosterone and reduce the insulin glargine dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin glargine
Frequently asked questions
Can I take Insulin glargine with Methyltestosterone?
MediHelp rates the interaction as moderate. Insulin glargine and Methyltestosterone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgens can improve insulin sensitivity and lower blood glucose, which may increase the risk of hypoglycemia in insulin-treated patients. The effect is usually modest but can matter when insulin doses are tightly titrated.
How serious is the interaction between Insulin glargine and Methyltestosterone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping methyltestosterone and reduce the insulin glargine dose if hypoglycemia occurs.
What other medicines interact with Insulin glargine?
MediHelp also lists interactions of Insulin glargine with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin glargine page.
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