Drug interactions
Ipratropium-salbutamol + Pseudoephedrine
Severity: Moderate
Ipratropium-salbutamol and Pseudoephedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pseudoephedrine and salbutamol are both sympathomimetics, and combined use can increase heart rate and blood pressure and cause tremor or palpitations. The risk is higher in patients with hypertension or heart disease.
What this interaction means in plain words
Ipratropium-salbutamol and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ipratropium-salbutamol belongs to Respiratory; Pseudoephedrine belongs to Respiratory.
Why it happens
Additive adrenergic stimulation.
What to do
Monitor blood pressure and heart rate, and avoid pseudoephedrine in patients with uncontrolled hypertension or cardiac disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Ipratropium-salbutamol with Pseudoephedrine?
MediHelp rates the interaction as moderate. Ipratropium-salbutamol and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pseudoephedrine and salbutamol are both sympathomimetics, and combined use can increase heart rate and blood pressure and cause tremor or palpitations. The risk is higher in patients with hypertension or heart disease.
How serious is the interaction between Ipratropium-salbutamol and Pseudoephedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, and avoid pseudoephedrine in patients with uncontrolled hypertension or cardiac disease.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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