Drug interactions
Ipratropium-salbutamol + Sunitinib
Severity: Moderate
Ipratropium-salbutamol and Sunitinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sunitinib can prolong the QT interval and salbutamol may add to this effect, particularly if hypokalemia is present. The risk is greatest in patients with cardiac disease or electrolyte disturbances.
What this interaction means in plain words
Ipratropium-salbutamol and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ipratropium-salbutamol belongs to Respiratory; Sunitinib belongs to Oncology.
Why it happens
Additive QT prolongation with possible beta-agonist-induced hypokalemia.
What to do
Monitor ECG and electrolytes, correct potassium and magnesium, and limit salbutamol to the lowest effective dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Sunitinib
- Adagrasib + Sunitinib Major
- Amiodarone + Sunitinib Major
- Amisulpride + Sunitinib Major
- Anagrelide + Sunitinib Major
- Apalutamide + Sunitinib Major
- Arsenic trioxide + Sunitinib Major
Frequently asked questions
Can I take Ipratropium-salbutamol with Sunitinib?
MediHelp rates the interaction as moderate. Ipratropium-salbutamol and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sunitinib can prolong the QT interval and salbutamol may add to this effect, particularly if hypokalemia is present. The risk is greatest in patients with cardiac disease or electrolyte disturbances.
How serious is the interaction between Ipratropium-salbutamol and Sunitinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes, correct potassium and magnesium, and limit salbutamol to the lowest effective dose.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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