Drug interactions
Isoproterenol + Pseudoephedrine
Severity: Moderate
Isoproterenol and Pseudoephedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Together they add to cardiac stimulation, increasing the risk of tachycardia, palpitations and arrhythmia. Isoproterenol is typically used in monitored settings.
What this interaction means in plain words
Isoproterenol and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Isoproterenol belongs to Respiratory; Pseudoephedrine belongs to Respiratory.
Why it happens
Additive adrenergic stimulation (beta-agonism with indirect sympathomimetic action).
What to do
Avoid pseudoephedrine in patients receiving isoproterenol; monitor ECG and heart rate if exposure occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Other interactions of Isoproterenol
Frequently asked questions
Can I take Isoproterenol with Pseudoephedrine?
MediHelp rates the interaction as moderate. Isoproterenol and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Together they add to cardiac stimulation, increasing the risk of tachycardia, palpitations and arrhythmia. Isoproterenol is typically used in monitored settings.
How serious is the interaction between Isoproterenol and Pseudoephedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid pseudoephedrine in patients receiving isoproterenol; monitor ECG and heart rate if exposure occurs.
What other medicines interact with Pseudoephedrine?
MediHelp also lists interactions of Pseudoephedrine with, for example, Isocarboxazid, Phenelzine, Rasagiline. The full list is on the Pseudoephedrine page.
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