Drug interactions
Isradipine + Mefloquine
Severity: Minor
Isradipine and Mefloquine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Isradipine is a dihydropyridine calcium channel blocker without a recognized QT-prolonging effect. Mefloquine can cause bradycardia and conduction effects, so additive hemodynamic or conduction effects are possible but not well documented.
What this interaction means in plain words
Isradipine and Mefloquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No well-established mechanism; possible additive effects on cardiac conduction and blood pressure.
What to do
No specific action is required beyond monitoring heart rate and blood pressure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mefloquine
- Arsenic trioxide + Mefloquine Contraindicated
- Dronedarone + Mefloquine Contraindicated
- Ibutilide + Mefloquine Contraindicated
- Levoketoconazole + Mefloquine Contraindicated
- Mefloquine + Nilotinib Contraindicated
- Mefloquine + Pimozide Contraindicated
Frequently asked questions
Can I take Isradipine with Mefloquine?
MediHelp rates the interaction as minor. Isradipine and Mefloquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Isradipine is a dihydropyridine calcium channel blocker without a recognized QT-prolonging effect. Mefloquine can cause bradycardia and conduction effects, so additive hemodynamic or conduction effects are possible but not well documented.
How serious is the interaction between Isradipine and Mefloquine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required beyond monitoring heart rate and blood pressure.
What other medicines interact with Mefloquine?
MediHelp also lists interactions of Mefloquine with, for example, Arsenic trioxide, Dronedarone, Ibutilide. The full list is on the Mefloquine page.
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