Drug interactions
itraconazole + rifampin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↓ itraconazole exposure; contraindicated.
Mechanism of action
Potent induction.
Clinical management
Contraindicated.
Drug reference
References
Frequently asked questions
Can I take itraconazole with rifampin?
The interaction is rated: Contraindicated. ↓ itraconazole exposure; contraindicated.
How serious is the interaction between itraconazole and rifampin?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between itraconazole and rifampin managed?
Contraindicated.
Why do itraconazole and rifampin interact?
Potent induction.
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