Drug interactions
Ketoprofen + Tafluprost
Severity: Minor
Ketoprofen and Tafluprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral NSAIDs and ophthalmic prostaglandin analogues act on related prostaglandin pathways, and conflicting reports describe either higher or lower intraocular pressure when combined. The effect is unpredictable and usually small.
What this interaction means in plain words
Ketoprofen and Tafluprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ketoprofen belongs to Musculoskeletal; Tafluprost belongs to Genitourinary.
Why it happens
NSAIDs inhibit prostaglandin synthesis, which may alter the uveoscleral outflow action of prostaglandin analogues; the mechanism is not well established.
What to do
Monitor intraocular pressure if an NSAID is started or stopped in a patient on tafluprost. No dose change is needed unless pressure control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Other interactions of Tafluprost
- Bimatoprost + Tafluprost Moderate
- Latanoprost + Tafluprost Moderate
- Tafluprost + Travoprost Moderate
- Acetylsalicylic acid + Tafluprost Minor
- Celecoxib + Tafluprost Minor
- Diclofenac + Tafluprost Minor
Frequently asked questions
Can I take Ketoprofen with Tafluprost?
MediHelp rates the interaction as minor. Ketoprofen and Tafluprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral NSAIDs and ophthalmic prostaglandin analogues act on related prostaglandin pathways, and conflicting reports describe either higher or lower intraocular pressure when combined. The effect is unpredictable and usually small.
How serious is the interaction between Ketoprofen and Tafluprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor intraocular pressure if an NSAID is started or stopped in a patient on tafluprost. No dose change is needed unless pressure control worsens.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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