Drug interactions
Ketorolac + Potassium iodide
Severity: Minor
Ketorolac and Potassium iodide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies potassium, and NSAIDs such as ketorolac can reduce renal potassium excretion. Hyperkalemia is possible, mainly with long-term use, renal impairment or other potassium-raising drugs.
What this interaction means in plain words
Ketorolac and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ketorolac belongs to Musculoskeletal; Potassium iodide belongs to Endocrine.
Why it happens
Additive potassium load with NSAID-related suppression of renin-aldosterone and reduced renal potassium excretion.
What to do
Check serum potassium and renal function in patients with renal impairment or on other potassium-raising drugs. No action needed for short, low-dose use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Ketorolac with Potassium iodide?
MediHelp rates the interaction as minor. Ketorolac and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Potassium iodide supplies potassium, and NSAIDs such as ketorolac can reduce renal potassium excretion. Hyperkalemia is possible, mainly with long-term use, renal impairment or other potassium-raising drugs.
How serious is the interaction between Ketorolac and Potassium iodide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium and renal function in patients with renal impairment or on other potassium-raising drugs. No action needed for short, low-dose use.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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