Drug interactions
Labetalol + Moxisylyte
Severity: Moderate
Labetalol and Moxisylyte: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxisylyte is an alpha-1 blocking vasodilator, and labetalol also blocks alpha-1 receptors in addition to beta receptors. Together they may cause additive vasodilation and hypotension, including orthostatic symptoms.
What this interaction means in plain words
Labetalol and Moxisylyte can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive alpha-adrenergic blockade producing vasodilation and lowered blood pressure.
What to do
Monitor blood pressure, including standing readings, when combining them. Counsel patients to rise slowly and lower the dose of either drug if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Labetalol
- Amifostine + Labetalol Major
- Amiodarone + Labetalol Major
- Atenolol-chlorthalidone + Labetalol Major
- Atenolol + Labetalol Major
- Betaxolol + Labetalol Major
- Bisoprolol + Labetalol Major
Frequently asked questions
Can I take Labetalol with Moxisylyte?
MediHelp rates the interaction as moderate. Labetalol and Moxisylyte can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxisylyte is an alpha-1 blocking vasodilator, and labetalol also blocks alpha-1 receptors in addition to beta receptors. Together they may cause additive vasodilation and hypotension, including orthostatic symptoms.
How serious is the interaction between Labetalol and Moxisylyte?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, including standing readings, when combining them. Counsel patients to rise slowly and lower the dose of either drug if hypotension develops.
What other medicines interact with Labetalol?
MediHelp also lists interactions of Labetalol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Labetalol page.
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