Drug interactions
Latanoprostene bunod + Travoprost
Severity: Moderate
Latanoprostene bunod and Travoprost: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Using more than one ophthalmic prostaglandin analog in the same eye has been associated with a reduced intraocular pressure lowering effect and occasionally paradoxical pressure increases. There is no benefit to combining them and the pair acts on the same receptor pathway.
What this interaction means in plain words
Latanoprostene bunod and Travoprost can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Both drugs act on the prostaglandin FP receptor and combined use may cause receptor-level interference; exact mechanism is not well established.
What to do
Use only one prostaglandin analog per eye; add a drug of another class (beta-blocker, carbonic anhydrase inhibitor, alpha agonist) if more pressure lowering is needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Travoprost
- Bimatoprost + Travoprost Moderate
- Latanoprost + Travoprost Moderate
- Tafluprost + Travoprost Moderate
- Celecoxib + Travoprost Minor
- Diclofenac + Travoprost Minor
- Etodolac + Travoprost Minor
Frequently asked questions
Can I take Latanoprostene bunod with Travoprost?
MediHelp rates the interaction as moderate. Latanoprostene bunod and Travoprost can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Using more than one ophthalmic prostaglandin analog in the same eye has been associated with a reduced intraocular pressure lowering effect and occasionally paradoxical pressure increases. There is no benefit to combining them and the pair acts on the same receptor pathway.
How serious is the interaction between Latanoprostene bunod and Travoprost?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only one prostaglandin analog per eye; add a drug of another class (beta-blocker, carbonic anhydrase inhibitor, alpha agonist) if more pressure lowering is needed.
What other medicines interact with Travoprost?
MediHelp also lists interactions of Travoprost with, for example, Bimatoprost, Latanoprost, Tafluprost. The full list is on the Travoprost page.
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