Drug interactions
Latanoprost + Travoprost
Severity: Moderate
Latanoprost and Travoprost: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Using two prostaglandin analogue eye drops together may fail to improve pressure lowering and has been reported to raise intraocular pressure paradoxically. There is no added benefit over a single agent.
What this interaction means in plain words
Latanoprost and Travoprost can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Latanoprost belongs to Miscellaneous; Travoprost belongs to Miscellaneous.
Why it happens
Not clearly established; possible receptor-level competition or down-regulation between agents of the same class.
What to do
Avoid using two prostaglandin analogues concurrently. Add an agent from a different class if more pressure lowering is needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Latanoprost
- Bimatoprost + Latanoprost Moderate
- Latanoprost + Latanoprostene bunod Moderate
- Latanoprost + Tafluprost Moderate
- Aspirin rectal + Latanoprost Minor
- Aspirin + Latanoprost Minor
- Bromfenac + Latanoprost Minor
Other interactions of Travoprost
- Bimatoprost + Travoprost Moderate
- Latanoprostene bunod + Travoprost Moderate
- Tafluprost + Travoprost Moderate
- Celecoxib + Travoprost Minor
- Diclofenac + Travoprost Minor
- Etodolac + Travoprost Minor
Frequently asked questions
Can I take Latanoprost with Travoprost?
MediHelp rates the interaction as moderate. Latanoprost and Travoprost can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Using two prostaglandin analogue eye drops together may fail to improve pressure lowering and has been reported to raise intraocular pressure paradoxically. There is no added benefit over a single agent.
How serious is the interaction between Latanoprost and Travoprost?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two prostaglandin analogues concurrently. Add an agent from a different class if more pressure lowering is needed.
What other medicines interact with Latanoprost?
MediHelp also lists interactions of Latanoprost with, for example, Bimatoprost, Latanoprostene bunod, Tafluprost. The full list is on the Latanoprost page.
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