Drug interactions
Diclofenac + Travoprost
Severity: Minor
Diclofenac and Travoprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reports on the effect of NSAIDs on the intraocular pressure response to prostaglandin analogues are inconsistent. Some data suggest a reduced pressure-lowering effect, others the opposite, and the clinical significance is uncertain.
What this interaction means in plain words
Diclofenac and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Diclofenac belongs to Musculoskeletal; Travoprost belongs to Miscellaneous.
Why it happens
No established mechanism; NSAIDs may interfere with prostaglandin-mediated uveoscleral outflow.
What to do
No routine change is needed; check intraocular pressure at follow-up visits if a systemic or ophthalmic NSAID is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Diclofenac
- Diclofenac + Ketorolac Contraindicated
- Diclofenac + Ketorolac intranasal Contraindicated
- Aceclofenac + Diclofenac Major
- Acemetacin + Diclofenac Major
- Alteplase + Diclofenac Major
- Amiloride + Diclofenac Major
Other interactions of Travoprost
- Bimatoprost + Travoprost Moderate
- Latanoprostene bunod + Travoprost Moderate
- Latanoprost + Travoprost Moderate
- Tafluprost + Travoprost Moderate
- Celecoxib + Travoprost Minor
- Etodolac + Travoprost Minor
Frequently asked questions
Can I take Diclofenac with Travoprost?
MediHelp rates the interaction as minor. Diclofenac and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reports on the effect of NSAIDs on the intraocular pressure response to prostaglandin analogues are inconsistent. Some data suggest a reduced pressure-lowering effect, others the opposite, and the clinical significance is uncertain.
How serious is the interaction between Diclofenac and Travoprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; check intraocular pressure at follow-up visits if a systemic or ophthalmic NSAID is started or stopped.
What other medicines interact with Diclofenac?
MediHelp also lists interactions of Diclofenac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Diclofenac page.
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