Drug interactions
Celecoxib + Travoprost
Severity: Minor
Celecoxib and Travoprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic NSAIDs may alter the intraocular pressure response to prostaglandin analogue eye drops, since both act on prostaglandin pathways. Published reports are inconsistent, with either a reduced or an enhanced pressure-lowering effect.
What this interaction means in plain words
Celecoxib and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Celecoxib belongs to Musculoskeletal; Travoprost belongs to Miscellaneous.
Why it happens
Possible pharmacodynamic opposition or modulation of prostaglandin-mediated aqueous humor outflow; the mechanism is not firmly established.
What to do
No empirical dose change is needed; check intraocular pressure at routine follow-up after starting or stopping celecoxib in a patient on travoprost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Other interactions of Travoprost
- Bimatoprost + Travoprost Moderate
- Latanoprostene bunod + Travoprost Moderate
- Latanoprost + Travoprost Moderate
- Tafluprost + Travoprost Moderate
- Diclofenac + Travoprost Minor
- Etodolac + Travoprost Minor
Frequently asked questions
Can I take Celecoxib with Travoprost?
MediHelp rates the interaction as minor. Celecoxib and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic NSAIDs may alter the intraocular pressure response to prostaglandin analogue eye drops, since both act on prostaglandin pathways. Published reports are inconsistent, with either a reduced or an enhanced pressure-lowering effect.
How serious is the interaction between Celecoxib and Travoprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose change is needed; check intraocular pressure at routine follow-up after starting or stopping celecoxib in a patient on travoprost.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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