Drug interactions
Levetiracetam + Oxazepam
Severity: Minor
Levetiracetam and Oxazepam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause drowsiness, dizziness and coordination problems, so combined use may increase these effects. Levetiracetam can also cause behavioural changes. No significant pharmacokinetic interaction is expected.
What this interaction means in plain words
Levetiracetam and Oxazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levetiracetam belongs to Central Nervous System; Oxazepam belongs to Central Nervous System.
Why it happens
Additive CNS effects through different mechanisms, GABA-A potentiation and SV2A binding.
What to do
Monitor for drowsiness and dizziness when starting or adjusting either drug. Counsel on driving and alcohol avoidance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxazepam
- Calcium / magnesium / potassium / sodium oxybates + Oxazepam Contraindicated
- Oxazepam + Sodium oxybate Contraindicated
- Alfentanil + Oxazepam Major
- Amobarbital + Oxazepam Major
- Baclofen + Oxazepam Major
- Belladonna and opium + Oxazepam Major
Other interactions of Levetiracetam
Frequently asked questions
Can I take Levetiracetam with Oxazepam?
MediHelp rates the interaction as minor. Levetiracetam and Oxazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause drowsiness, dizziness and coordination problems, so combined use may increase these effects. Levetiracetam can also cause behavioural changes. No significant pharmacokinetic interaction is expected.
How serious is the interaction between Levetiracetam and Oxazepam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for drowsiness and dizziness when starting or adjusting either drug. Counsel on driving and alcohol avoidance.
What other medicines interact with Oxazepam?
MediHelp also lists interactions of Oxazepam with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Oxazepam page.
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