Drug interactions
Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate + Moxifloxacin
Severity: Minor
Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate and Moxifloxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Evidence that non-rifamycin antibiotics reduce the efficacy of combined oral contraceptives is weak, and the effect is considered unlikely to be clinically meaningful. The iron component of this product could in theory chelate moxifloxacin and reduce its absorption.
What this interaction means in plain words
Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical gut flora effect on estrogen recirculation, and possible iron chelation of moxifloxacin in the gut.
What to do
Separate the iron-containing tablets from oral moxifloxacin by at least 4 hours before or 8 hours after. Extra contraception is not routinely needed, but advise it if vomiting or diarrhea occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate with Moxifloxacin?
MediHelp rates the interaction as minor. Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Evidence that non-rifamycin antibiotics reduce the efficacy of combined oral contraceptives is weak, and the effect is considered unlikely to be clinically meaningful. The iron component of this product could in theory chelate moxifloxacin and reduce its absorption.
How serious is the interaction between Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate and Moxifloxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate the iron-containing tablets from oral moxifloxacin by at least 4 hours before or 8 hours after. Extra contraception is not routinely needed, but advise it if vomiting or diarrhea occurs.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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