Drug interactions
Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate + Rosuvastatin
Severity: Minor
Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate and Rosuvastatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rosuvastatin modestly increases ethinylestradiol exposure, by roughly a fifth to a quarter. This is usually of little clinical consequence but may slightly increase estrogenic adverse effects.
What this interaction means in plain words
Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate and Rosuvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
The mechanism is not well established; rosuvastatin may alter ethinylestradiol handling through transporter or conjugation effects.
What to do
No dose adjustment is needed; be aware of possible increased estrogenic effects such as nausea or breast tenderness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosuvastatin
Frequently asked questions
Can I take Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate with Rosuvastatin?
MediHelp rates the interaction as minor. Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate and Rosuvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rosuvastatin modestly increases ethinylestradiol exposure, by roughly a fifth to a quarter. This is usually of little clinical consequence but may slightly increase estrogenic adverse effects.
How serious is the interaction between Levonorgestrel oral / ethinylestradiol / ferrous bisglycinate and Rosuvastatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; be aware of possible increased estrogenic effects such as nausea or breast tenderness.
What other medicines interact with Rosuvastatin?
MediHelp also lists interactions of Rosuvastatin with, for example, Atazanavir, Cyclosporine, Cyclosporin. The full list is on the Rosuvastatin page.
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