Drug interactions
Liraglutide + Perindopril
Severity: Minor
Liraglutide and Perindopril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors may slightly increase glucose-lowering effects of antidiabetic agents. With liraglutide alone the hypoglycemia risk is low, but a small additive effect on glycemic control is possible.
What this interaction means in plain words
Liraglutide and Perindopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Liraglutide belongs to Endocrine; Perindopril belongs to Cardiovascular.
Why it happens
Possible improvement in insulin sensitivity by ACE inhibition; the mechanism is not firmly established.
What to do
Routine glucose monitoring is sufficient; watch more closely if a sulfonylurea or insulin is also used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Perindopril
- Aliskiren + Perindopril Contraindicated
- Perindopril + Protein a column Contraindicated
- Perindopril + Sacubitril / valsartan Contraindicated
- Perindopril + Sacubitril-valsartan Contraindicated
- Amifostine + Perindopril Major
- Amiloride + Perindopril Major
Other interactions of Liraglutide
Frequently asked questions
Can I take Liraglutide with Perindopril?
MediHelp rates the interaction as minor. Liraglutide and Perindopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors may slightly increase glucose-lowering effects of antidiabetic agents. With liraglutide alone the hypoglycemia risk is low, but a small additive effect on glycemic control is possible.
How serious is the interaction between Liraglutide and Perindopril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Routine glucose monitoring is sufficient; watch more closely if a sulfonylurea or insulin is also used.
What other medicines interact with Perindopril?
MediHelp also lists interactions of Perindopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Perindopril page.
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