Drug interactions
Losartan + Maitake
Severity: Minor
Losartan and Maitake: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom has been reported in animal and small studies to lower blood pressure, so it could add to the effect of losartan. Evidence in humans is sparse, and clinically important hypotension is not well documented.
What this interaction means in plain words
Losartan and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive blood pressure lowering; mechanism for maitake is not firmly established.
What to do
Monitor blood pressure if the patient takes maitake supplements regularly, and reduce the losartan dose if symptomatic hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Losartan
- Aliskiren + Losartan Contraindicated
- Losartan + Sparsentan Contraindicated
- Amifostine + Losartan Major
- Amiloride + Losartan Major
- Amlodipine-benazepril + Losartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Losartan Major
Frequently asked questions
Can I take Losartan with Maitake?
MediHelp rates the interaction as minor. Losartan and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom has been reported in animal and small studies to lower blood pressure, so it could add to the effect of losartan. Evidence in humans is sparse, and clinically important hypotension is not well documented.
How serious is the interaction between Losartan and Maitake?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if the patient takes maitake supplements regularly, and reduce the losartan dose if symptomatic hypotension develops.
What other medicines interact with Losartan?
MediHelp also lists interactions of Losartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Losartan page.
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