Drug interactions
Losartan + Shepherd's purse
Severity: Minor
Losartan and Shepherd's purse: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shepherd's purse has been reported to affect blood pressure and vascular tone, so it may unpredictably alter the antihypertensive response to losartan. Evidence is theoretical.
What this interaction means in plain words
Losartan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible pharmacodynamic opposition or variability of blood pressure effect; mechanism is not established.
What to do
Advise patients to avoid the herb where possible and check blood pressure if it is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Losartan
- Aliskiren + Losartan Contraindicated
- Losartan + Sparsentan Contraindicated
- Amifostine + Losartan Major
- Amiloride + Losartan Major
- Amlodipine-benazepril + Losartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Losartan Major
Frequently asked questions
Can I take Losartan with Shepherd's purse?
MediHelp rates the interaction as minor. Losartan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shepherd's purse has been reported to affect blood pressure and vascular tone, so it may unpredictably alter the antihypertensive response to losartan. Evidence is theoretical.
How serious is the interaction between Losartan and Shepherd's purse?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid the herb where possible and check blood pressure if it is used.
What other medicines interact with Losartan?
MediHelp also lists interactions of Losartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Losartan page.
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