Drug interactions
Lurasidone + Meclizine
Severity: Minor
Lurasidone and Meclizine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause drowsiness and dizziness, so combined use may increase sedation and impair alertness. Meclizine's anticholinergic activity may add to antipsychotic side effects such as constipation and blurred vision.
What this interaction means in plain words
Lurasidone and Meclizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lurasidone belongs to Central Nervous System; Meclizine belongs to Respiratory.
Why it happens
Additive CNS depression and anticholinergic effects.
What to do
Use the lowest effective meclizine dose and advise patients to avoid driving if drowsy; monitor older adults for confusion and falls.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Other interactions of Meclizine
Frequently asked questions
Can I take Lurasidone with Meclizine?
MediHelp rates the interaction as minor. Lurasidone and Meclizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause drowsiness and dizziness, so combined use may increase sedation and impair alertness. Meclizine's anticholinergic activity may add to antipsychotic side effects such as constipation and blurred vision.
How serious is the interaction between Lurasidone and Meclizine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective meclizine dose and advise patients to avoid driving if drowsy; monitor older adults for confusion and falls.
What other medicines interact with Lurasidone?
MediHelp also lists interactions of Lurasidone with, for example, Apalutamide, Atazanavir, Carbamazepine. The full list is on the Lurasidone page.
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