Drug interactions
Lurasidone + Quazepam
Severity: Moderate
Lurasidone and Quazepam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lurasidone and the benzodiazepine quazepam both depress the central nervous system. Together they can intensify drowsiness, dizziness and impaired coordination and judgment. Older or frail patients are at greater risk of falls.
What this interaction means in plain words
Lurasidone and Quazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depressant effects of an antipsychotic and a benzodiazepine hypnotic.
What to do
Monitor for oversedation and impaired psychomotor function, using the lowest effective quinazepam dose. Advise avoiding alcohol and other sedatives.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Frequently asked questions
Can I take Lurasidone with Quazepam?
MediHelp rates the interaction as moderate. Lurasidone and Quazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lurasidone and the benzodiazepine quazepam both depress the central nervous system. Together they can intensify drowsiness, dizziness and impaired coordination and judgment. Older or frail patients are at greater risk of falls.
How serious is the interaction between Lurasidone and Quazepam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for oversedation and impaired psychomotor function, using the lowest effective quinazepam dose. Advise avoiding alcohol and other sedatives.
What other medicines interact with Lurasidone?
MediHelp also lists interactions of Lurasidone with, for example, Apalutamide, Atazanavir, Carbamazepine. The full list is on the Lurasidone page.
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