Drug interactions

lurasidone + rifampin

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Severity: Contraindicated · Evidence level: High

↓ lurasidone exposure; contraindicated.

Mechanism of action

Strong CYP3A induction.

Clinical management

Contraindicated.

Drug reference

References

Frequently asked questions

Can I take lurasidone with rifampin?

The interaction is rated: Contraindicated. ↓ lurasidone exposure; contraindicated.

How serious is the interaction between lurasidone and rifampin?

The interaction is rated: Contraindicated. Evidence level: High.

How is the interaction between lurasidone and rifampin managed?

Contraindicated.

Why do lurasidone and rifampin interact?

Strong CYP3A induction.

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