Drug interactions
Magnesium + Triamterene
Severity: Minor
Magnesium and Triamterene: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triamterene is a potassium-sparing diuretic that tends to reduce urinary magnesium loss. Serum magnesium may rise slightly, which is seldom significant except in renal impairment with magnesium supplementation.
What this interaction means in plain words
Magnesium and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Magnesium belongs to Gastrointestinal Tract; Triamterene belongs to Cardiovascular.
Why it happens
Blockade of epithelial sodium channels in the distal nephron may reduce renal magnesium wasting.
What to do
No routine action is needed. Check serum magnesium in patients with reduced renal function who take magnesium supplements with triamterene.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium
- Ciprofloxacin + Magnesium Major
- Magnesium + Pancuronium Major
- Magnesium + Rocuronium Major
- Magnesium + Vecuronium Major
- Amikacin + Magnesium Moderate
- Amphotericin b deoxycholate + Magnesium Moderate
Other interactions of Triamterene
- Amiloride + Triamterene Contraindicated
- Eplerenone + Triamterene Contraindicated
- Potassium citrate / citric acid + Triamterene Contraindicated
- Potassium citrate + Triamterene Contraindicated
- Spironolactone + Triamterene Contraindicated
- Aceclofenac + Triamterene Major
Frequently asked questions
Can I take Magnesium with Triamterene?
MediHelp rates the interaction as minor. Magnesium and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Triamterene is a potassium-sparing diuretic that tends to reduce urinary magnesium loss. Serum magnesium may rise slightly, which is seldom significant except in renal impairment with magnesium supplementation.
How serious is the interaction between Magnesium and Triamterene?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Check serum magnesium in patients with reduced renal function who take magnesium supplements with triamterene.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
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