Drug interactions
Marijuana + Rosiglitazone
Severity: Minor
Marijuana and Rosiglitazone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cannabis may increase appetite and affect glucose regulation, which might worsen glycemic control. Evidence for a direct effect on rosiglitazone is limited and inconsistent.
What this interaction means in plain words
Marijuana and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible pharmacodynamic antagonism via increased appetite and altered glucose metabolism; not firmly established.
What to do
Monitor glucose control in regular cannabis users. Counsel on diet and adherence.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Major
- Insulin aspart-insulin aspart protamine + Rosiglitazone Major
- Insulin aspart + Rosiglitazone Major
- Insulin degludec / insulin aspart + Rosiglitazone Major
- Insulin degludec-insulin aspart + Rosiglitazone Major
- Insulin degludec-liraglutide + Rosiglitazone Major
Frequently asked questions
Can I take Marijuana with Rosiglitazone?
MediHelp rates the interaction as minor. Marijuana and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cannabis may increase appetite and affect glucose regulation, which might worsen glycemic control. Evidence for a direct effect on rosiglitazone is limited and inconsistent.
How serious is the interaction between Marijuana and Rosiglitazone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose control in regular cannabis users. Counsel on diet and adherence.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart protamine / insulin aspart, Insulin aspart-insulin aspart protamine, Insulin aspart. The full list is on the Rosiglitazone page.
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