Drug interactions
Meclizine + Succinylcholine
Severity: Minor
Meclizine and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Meclizine is a sedating antihistamine with mild anticholinergic activity and has no recognized effect on succinylcholine's neuromuscular action. Any additive sedation is minor and does not alter blockade.
What this interaction means in plain words
Meclizine and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Meclizine belongs to Respiratory; Succinylcholine belongs to Musculoskeletal.
Why it happens
No established pharmacokinetic or neuromuscular interaction.
What to do
No specific action is required. Monitor sedation level during anesthesia recovery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Succinylcholine
Other interactions of Meclizine
Frequently asked questions
Can I take Meclizine with Succinylcholine?
MediHelp rates the interaction as minor. Meclizine and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Meclizine is a sedating antihistamine with mild anticholinergic activity and has no recognized effect on succinylcholine's neuromuscular action. Any additive sedation is minor and does not alter blockade.
How serious is the interaction between Meclizine and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required. Monitor sedation level during anesthesia recovery.
What other medicines interact with Succinylcholine?
MediHelp also lists interactions of Succinylcholine with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Succinylcholine page.
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