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Drug interactions

Meperidine + Motherwort

Severity: Minor

Meperidine and Motherwort: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Motherwort has traditional sedative properties and may add to opioid-induced drowsiness. Clinical data are scarce.

What this interaction means in plain words

Meperidine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive sedation; the mechanism of motherwort's effect is not well established.

What to do

Counsel patients about additive drowsiness and avoid driving until response is known. Consider stopping the herbal product if sedation is excessive.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Meperidine with Motherwort?

MediHelp rates the interaction as minor. Meperidine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort has traditional sedative properties and may add to opioid-induced drowsiness. Clinical data are scarce.

How serious is the interaction between Meperidine and Motherwort?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about additive drowsiness and avoid driving until response is known. Consider stopping the herbal product if sedation is excessive.

What other medicines interact with Meperidine?

MediHelp also lists interactions of Meperidine with, for example, Alvimopan, Isocarboxazid, Methylene blue. The full list is on the Meperidine page.

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