Drug interactions
Metaproterenol + Nabilone
Severity: Minor
Metaproterenol and Nabilone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can raise heart rate, and nabilone commonly causes tachycardia and orthostatic changes, while metaproterenol is a beta-agonist that may cause tachycardia and palpitations. The sedation effect of nabilone is not meaningfully countered by metaproterenol.
What this interaction means in plain words
Metaproterenol and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive cardiovascular stimulation (tachycardia) from cannabinoid effects and beta-adrenergic agonism; no established pharmacokinetic mechanism.
What to do
Monitor heart rate and symptoms such as palpitations, particularly in patients with cardiac disease. No dose change is usually needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nabilone
Frequently asked questions
Can I take Metaproterenol with Nabilone?
MediHelp rates the interaction as minor. Metaproterenol and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can raise heart rate, and nabilone commonly causes tachycardia and orthostatic changes, while metaproterenol is a beta-agonist that may cause tachycardia and palpitations. The sedation effect of nabilone is not meaningfully countered by metaproterenol.
How serious is the interaction between Metaproterenol and Nabilone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and symptoms such as palpitations, particularly in patients with cardiac disease. No dose change is usually needed.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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