Drug interactions
Metaproterenol + Piroxicam
Severity: Minor
Metaproterenol and Piroxicam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The clinical significance is unclear. Metaproterenol can lower serum potassium, whereas NSAIDs may raise it through reduced renal potassium excretion, so effects may partly offset each other.
What this interaction means in plain words
Metaproterenol and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing effects on serum potassium: beta-agonist driven intracellular shift versus NSAID-related reduced renal potassium excretion; the net effect is not well established.
What to do
No routine action is required. Check serum potassium if high doses of metaproterenol are used or the patient has renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Piroxicam
- Ketorolac intranasal + Piroxicam Contraindicated
- Ketorolac + Piroxicam Contraindicated
- Aceclofenac + Piroxicam Major
- Acemetacin + Piroxicam Major
- Acetylsalicylic acid + Piroxicam Major
- Alteplase + Piroxicam Major
Frequently asked questions
Can I take Metaproterenol with Piroxicam?
MediHelp rates the interaction as minor. Metaproterenol and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The clinical significance is unclear. Metaproterenol can lower serum potassium, whereas NSAIDs may raise it through reduced renal potassium excretion, so effects may partly offset each other.
How serious is the interaction between Metaproterenol and Piroxicam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is required. Check serum potassium if high doses of metaproterenol are used or the patient has renal impairment.
What other medicines interact with Piroxicam?
MediHelp also lists interactions of Piroxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Piroxicam page.
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