Drug interactions
Metaproterenol + Succinylcholine
Severity: Minor
Metaproterenol and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Succinylcholine may raise serum potassium while metaproterenol tends to lower it. The net effect is unclear and clinically significant harm is not well documented.
What this interaction means in plain words
Metaproterenol and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing effects on serum potassium: depolarization-induced release versus beta-2 mediated cellular uptake.
What to do
No routine change is needed. Monitor serum potassium and ECG in patients with high-dose beta-agonist exposure or other arrhythmia risks.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Succinylcholine
Frequently asked questions
Can I take Metaproterenol with Succinylcholine?
MediHelp rates the interaction as minor. Metaproterenol and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Succinylcholine may raise serum potassium while metaproterenol tends to lower it. The net effect is unclear and clinically significant harm is not well documented.
How serious is the interaction between Metaproterenol and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor serum potassium and ECG in patients with high-dose beta-agonist exposure or other arrhythmia risks.
What other medicines interact with Succinylcholine?
MediHelp also lists interactions of Succinylcholine with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Succinylcholine page.
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