Drug interactions
Metformin-repaglinide + Nimodipine
Severity: Minor
Metformin-repaglinide and Nimodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dihydropyridine calcium channel blockers may slightly impair glucose tolerance, so nimodipine could weaken glycemic control. The clinical effect is usually small.
What this interaction means in plain words
Metformin-repaglinide and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Metformin-repaglinide belongs to Endocrine; Nimodipine belongs to Cardiovascular.
Why it happens
Calcium channel blockade may reduce insulin secretion; the mechanism is not firmly established.
What to do
Check blood glucose when nimodipine is started or stopped in patients with unstable control; no routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Frequently asked questions
Can I take Metformin-repaglinide with Nimodipine?
MediHelp rates the interaction as minor. Metformin-repaglinide and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dihydropyridine calcium channel blockers may slightly impair glucose tolerance, so nimodipine could weaken glycemic control. The clinical effect is usually small.
How serious is the interaction between Metformin-repaglinide and Nimodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose when nimodipine is started or stopped in patients with unstable control; no routine dose change is needed.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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