Drug interactions
Methyl aminolevulinate + Moxifloxacin
Severity: Moderate
Methyl aminolevulinate and Moxifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxifloxacin can cause photosensitivity, and methyl aminolevulinate is a topical photosensitizer used in photodynamic therapy. Systemic absorption of the topical agent is minimal, so a meaningful interaction is uncertain, though additive skin phototoxicity is possible.
What this interaction means in plain words
Methyl aminolevulinate and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive phototoxicity from two photosensitizing agents.
What to do
Counsel patients to avoid sun exposure and consider delaying photodynamic therapy until the fluoroquinolone course is done. Monitor treated skin for exaggerated reactions.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Methyl aminolevulinate with Moxifloxacin?
MediHelp rates the interaction as moderate. Methyl aminolevulinate and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxifloxacin can cause photosensitivity, and methyl aminolevulinate is a topical photosensitizer used in photodynamic therapy. Systemic absorption of the topical agent is minimal, so a meaningful interaction is uncertain, though additive skin phototoxicity is possible.
How serious is the interaction between Methyl aminolevulinate and Moxifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid sun exposure and consider delaying photodynamic therapy until the fluoroquinolone course is done. Monitor treated skin for exaggerated reactions.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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