Drug interactions
Methyl aminolevulinate + Voriconazole
Severity: Moderate
Methyl aminolevulinate and Voriconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole is associated with phototoxicity and photosensitivity, which could add to the photosensitizing effect of methyl aminolevulinate photodynamic therapy. Topical use limits systemic exposure but local reactions could be heightened.
What this interaction means in plain words
Methyl aminolevulinate and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive photosensitizing effects, which are theoretical for topical methyl aminolevulinate.
What to do
Counsel strict sun protection and watch for exaggerated local phototoxic reactions after treatment. Consider deferring photodynamic therapy if voriconazole is not essential.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Methyl aminolevulinate and Voriconazole, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Methyl aminolevulinate with Voriconazole?
MediHelp rates the interaction as moderate. Methyl aminolevulinate and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voriconazole is associated with phototoxicity and photosensitivity, which could add to the photosensitizing effect of methyl aminolevulinate photodynamic therapy. Topical use limits systemic exposure but local reactions could be heightened.
How serious is the interaction between Methyl aminolevulinate and Voriconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel strict sun protection and watch for exaggerated local phototoxic reactions after treatment. Consider deferring photodynamic therapy if voriconazole is not essential.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
