Drug interactions
Metoprolol + Olmesartan
Severity: Minor
Metoprolol and Olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Together they lower blood pressure additively, which is often desired. Olmesartan can raise serum potassium, whereas metoprolol has minimal effect. Olmesartan is contraindicated in pregnancy.
What this interaction means in plain words
Metoprolol and Olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Metoprolol belongs to Cardiovascular; Olmesartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects; ARB-related reduction of aldosterone-mediated potassium excretion.
What to do
Monitor blood pressure and heart rate when starting or adjusting therapy. Check potassium and renal function periodically.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metoprolol
- Metoprolol + Thioridazine Contraindicated
- Amifostine + Metoprolol Major
- Amiodarone + Metoprolol Major
- Atenolol-chlorthalidone + Metoprolol Major
- Atenolol + Metoprolol Major
- Betaxolol + Metoprolol Major
Other interactions of Olmesartan
- Aliskiren + Olmesartan Contraindicated
- Olmesartan + Sparsentan Contraindicated
- Aldesleukin + Olmesartan Major
- Amifostine + Olmesartan Major
- Amiloride + Olmesartan Major
- Amlodipine-benazepril + Olmesartan Major
Frequently asked questions
Can I take Metoprolol with Olmesartan?
MediHelp rates the interaction as minor. Metoprolol and Olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Together they lower blood pressure additively, which is often desired. Olmesartan can raise serum potassium, whereas metoprolol has minimal effect. Olmesartan is contraindicated in pregnancy.
How serious is the interaction between Metoprolol and Olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting therapy. Check potassium and renal function periodically.
What other medicines interact with Metoprolol?
MediHelp also lists interactions of Metoprolol with, for example, Thioridazine, Amifostine, Amiodarone. The full list is on the Metoprolol page.
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