Drug interactions
Moexipril + Treprostinil
Severity: Moderate
Moexipril and Treprostinil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Treprostinil is a potent vasodilator, so combining it with moexipril may produce additive blood pressure lowering. Symptomatic hypotension is possible, particularly at initiation or dose increases.
What this interaction means in plain words
Moexipril and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Moexipril belongs to Cardiovascular; Treprostinil belongs to Cardiovascular.
Why it happens
Additive vasodilation and blood pressure reduction through different pathways.
What to do
Monitor blood pressure and symptoms of hypotension when starting or titrating either drug. Reduce the moexipril dose if hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Other interactions of Treprostinil
Frequently asked questions
Can I take Moexipril with Treprostinil?
MediHelp rates the interaction as moderate. Moexipril and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Treprostinil is a potent vasodilator, so combining it with moexipril may produce additive blood pressure lowering. Symptomatic hypotension is possible, particularly at initiation or dose increases.
How serious is the interaction between Moexipril and Treprostinil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and symptoms of hypotension when starting or titrating either drug. Reduce the moexipril dose if hypotension occurs.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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