Drug interactions
Mometasone inhaled + Moxifloxacin
Severity: Minor
Mometasone inhaled and Moxifloxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoroquinolone-associated tendon rupture risk is increased by systemic corticosteroids. Inhaled mometasone has low systemic exposure, so the added risk is small.
What this interaction means in plain words
Mometasone inhaled and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive tendon toxicity, with limited steroid contribution because of low systemic absorption.
What to do
No dose change needed. Advise patients to stop moxifloxacin and seek review if tendon pain develops, especially if high-dose steroid is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Mometasone inhaled with Moxifloxacin?
MediHelp rates the interaction as minor. Mometasone inhaled and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluoroquinolone-associated tendon rupture risk is increased by systemic corticosteroids. Inhaled mometasone has low systemic exposure, so the added risk is small.
How serious is the interaction between Mometasone inhaled and Moxifloxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change needed. Advise patients to stop moxifloxacin and seek review if tendon pain develops, especially if high-dose steroid is used.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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