Drug interactions
Mometasone intranasal + Voriconazole
Severity: Minor
Mometasone intranasal and Voriconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole may increase systemic exposure to mometasone from nasal use, though systemic absorption is low. Prolonged use theoretically raises the risk of corticosteroid effects such as adrenal suppression.
What this interaction means in plain words
Mometasone intranasal and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Voriconazole inhibits CYP3A4 metabolism of absorbed mometasone.
What to do
Usually no action is required for short courses. Monitor for signs of systemic corticosteroid excess with prolonged co-use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Mometasone intranasal with Voriconazole?
MediHelp rates the interaction as minor. Mometasone intranasal and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voriconazole may increase systemic exposure to mometasone from nasal use, though systemic absorption is low. Prolonged use theoretically raises the risk of corticosteroid effects such as adrenal suppression.
How serious is the interaction between Mometasone intranasal and Voriconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Usually no action is required for short courses. Monitor for signs of systemic corticosteroid excess with prolonged co-use.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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