Drug interactions
Motherwort + Nabilone
Severity: Moderate
Motherwort and Nabilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Motherwort has traditional sedative properties and may add to the drowsiness caused by nabilone. The effect is predicted rather than well documented.
What this interaction means in plain words
Motherwort and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Presumed additive CNS depression from the herbal sedative and the cannabinoid.
What to do
Advise patients to avoid or limit motherwort while taking nabilone, and monitor for excessive drowsiness.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Frequently asked questions
Can I take Motherwort with Nabilone?
MediHelp rates the interaction as moderate. Motherwort and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Motherwort has traditional sedative properties and may add to the drowsiness caused by nabilone. The effect is predicted rather than well documented.
How serious is the interaction between Motherwort and Nabilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid or limit motherwort while taking nabilone, and monitor for excessive drowsiness.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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