Drug interactions
Moxifloxacin + Olodaterol inhaled
Severity: Moderate
Moxifloxacin and Olodaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olodaterol is a long-acting beta2 agonist that may prolong the QT interval and lower potassium, and moxifloxacin adds its own QT effect. The combination may raise the risk of ventricular arrhythmias, especially in people with heart disease.
What this interaction means in plain words
Moxifloxacin and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta2-agonist-induced hypokalemia and sympathetic stimulation.
What to do
Monitor the ECG and serum potassium in patients with cardiac disease or other QT risk factors. Consider an alternative antibiotic if risk is high.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Moxifloxacin with Olodaterol inhaled?
MediHelp rates the interaction as moderate. Moxifloxacin and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Olodaterol is a long-acting beta2 agonist that may prolong the QT interval and lower potassium, and moxifloxacin adds its own QT effect. The combination may raise the risk of ventricular arrhythmias, especially in people with heart disease.
How serious is the interaction between Moxifloxacin and Olodaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the ECG and serum potassium in patients with cardiac disease or other QT risk factors. Consider an alternative antibiotic if risk is high.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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